Ottavio "Tai" Missoni was born in 1921 in Ragusa, in what is now Croatia. As a young man, he was a champion runner.
It 1947, he began a business designing men's athletic wear. His designs were used the next year by the Italian Olympic team. Missoni was on the Italian Olympic track team that year.
He married his wife Rosita in 1953, and they continued his knitwear business together. The business expanded enough that by 1966 they were able to put forth their first collection showing. In 1967, their collection made headlines when Rosita told the models right before the show to take off their brassieres, because they ruined the lines of the dresses. The lights made the dresses transparent, shocking the fashion press.
Missoni was renowned for its excellence in knitwear, although the design house was also a leading innovator in using patchworks, and they received the Neiman Marcus Fashion Award in 1973, the same year as Missoni creations first entered the collections of leading art museums.
Missoni was named among the 10 most important European designers by Vogue in 1975. Missoni presented its first menswear collection in 1979, and in 1981 expanded into fabrics for furniture.
Rosita and Tai both received the Commendatore al Merito from the President of Italy. Rosita received the International Design Award from the Fashion Group International. Tai and Rosita have been joined in the management of the business by their three children, Vittorio, Luca, and Angela. Vittorio is the marketing director, while Luca and Angela are in charge of menswear and womenswear designs, respectively.
Missoni creations are notable for their use of color and pattern, often using rainbow stripes and zigzags.